John Wayne Casserole Recipe: A Ground Beef Casserole Recipe Courtesy of The Duke by Donna John

John Wayne Casserole Recipe: A Ground Beef Casserole Recipe Courtesy of The Duke

Casseroles are so easy to throw together during the week, and can be reheated easily for leftovers. A win-win. This John Wayne Casserole recipe is simple to make and a hearty dinner, just as you'd expect from The Duke.

John Wayne was born Marion Robert Morrison in 1907. While there are many stories out there about why his nickname was The Duke, most are not true. John Wayne actually got his nickname because of his beloved dog, Duke, when he was a kid.

All you need to make this casserole is ground beef, taco seasoning, refrigerated biscuit dough, sour cream, mayonnaise, onion, cheddar cheese, red bell pepper, a tomato and pickled jalapenos. Serve this ground beef recipe with a fresh vegetable or salad on the side.

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Cuisine: American
Prep Time: 20 minutes
Cook Time: 50 minutes
Total Time: 1 hour and 10 minutes
Servings: 8


  • 2 pounds ground beef
  • 1 packet (1 ounce) taco seasoning
  • 1 can (16 ounces) large refrigerated biscuits
  • 1/2 cup sour cream
  • 1/2 cup mayonnaise
  • 8 ounces grated cheddar cheese (divided)
  • 1 onion, chopped (divided)
  • 1 red bell pepper, chopped
  • 1 large tomato, sliced
  • 4 ounces sliced pickled jalapenos

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Recipe Notes

  • I divided the ingredients in two, using a casserole dish and a disposable 8x8-inch baking pan a lid so I could freeze one for later.
  • You could use fresh sliced jalapenos instead of pickled jalapenos. Remove the ribs and seeds for less heat.
  • Monterey Jack, colby-jack, pepper-jack or your favorite Mexican cheese blend can be used instead of cheddar cheese.

Here's how to make it: 

  1. Put the biscuits in a single layer in a 13x9-inch casserole dish that's been sprayed with nonstick cooking spray. Press them onto the bottom and halfway up the sides, sealing them together, to form the crust. 
  2. Bake in a preheated 350-degree F oven for about 12 to 14 minutes or until very light brown. Remove and set aside.
  3. In a skillet, cook the ground beef until cooked through. Add the taco seasoning and water according to taco seasoning package directions. Once the liquid has evaporated, add half of the onions and red bell pepper. Cook until soft, about 3 minutes.
  4. In a small bowl, combine the sour cream, mayonnaise, half of the cheddar cheese and remaining onions (raw). 
  5. Layer the ingredients in the following order on the biscuit dough: taco meat, tomato slices, onion mixture, jalapenos, sour cream mixture and remaining cheddar cheese.
  6. Bake for about 30 minutes. 

Nutrition Facts Per Serving

Calories: 705

Total Fat: 35.5g

Saturated Fat: 16.5g

Cholesterol: 239mg

Sodium: 1571mg

Total Carbohydrate: 16.5g

Dietary Fiber: 2.4g

Total Sugars: 2.7g

Protein: 74.6g

Vitamin D: 3mcg

Calcium: 248mg

Iron: 8mg

Potassium: 1157mg

Recipe cooking times, nutritional information and servings are approximate and provided for your convenience. However, 30Seconds is not responsible for the outcome of any recipe, nor may you have the same results because of variations in ingredients, temperatures, altitude, errors, omissions or cooking/baking abilities. This recipe has been analyzed by VeryWellFit. However, any nutritional information is provided as a courtesy and it is up to the individual to ascertain accuracy. To ensure image quality, we may occasionally use stock photography.

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Love the Duke, RIP. What a great recipe to remember him by.
One of my favorites! I have his cookbook!
Donna John
It's a great cookbook!
Elisa Schmitz
What a delicious recipe, Donna John . Has all the old-fashioned comfort food feels, plus who wouldn't want to try a recipe by John Wayne? So cool!
Allie Frank
Is the onion mixture the same as the sour cream mixture? Where did that part come from?
Donna John
In a small bowl, combine the sour cream, mayonnaise, half of the cheddar cheese and remaining onions (raw). This is step four. It's the same thing.

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